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Inosine glucose injection

Product description
Approved date: November 14, 2006
 
Date of revision: November 15, 2014
 
          November 30, 2015
 
          December 31, 2018
 
 
 
Inosine glucose injection instructions
 
 Please read the instructions carefully and use them under the guidance of a physician.
 
【Drug Name】
 
Generic Name: Inosine Glucose Injection
 
Product Name :Pedigan
 
English name: Inosine and Glucose Injection
 
Pinyin: Jigan Putaotang Zhusheye
 
[Ingredients] The main component of this product is inosine, and its chemical name is 9β-D-ribose hypoxanthine.
 
 
 
Molecular formula: C10H12N4O5
 
Molecular weight: 268.23
 
The excipient is: glucose.
 
【Properties】 This product is a colorless clear liquid.
 
[Indications] Coenzymes have the effect of improving the body's metabolism. It is used for adjuvant treatment of leukopenia and thrombocytopenia, heart failure, angina pectoris, hepatitis, etc. caused by various causes. Can also be used for optic nerve atrophy, adjuvant treatment of central retinitis.
 
[Specifications] (1) 250ml: Inosine 0.6g and glucose 12.5g; (2) 100ml: Inosine 0.6g and glucose 5.0g
 
[Usage and dosage] intravenous drip. 0.2 to 0.6 g each time (in terms of inosine), 1 to 2 times a day.
 
[Adverse reactions] Occasionally, facial flushing, nausea, chest burning and so on.
 
[Contraindications] Disabled for allergic to this product.
 
【Precautions】
 
1. Intravenous infusion of this product has caused reports of cardiac arrest and death from anaphylactic shock. It is recommended to slowly instill and closely observe changes in vital signs and allergic reactions.
 
2. Before using this product, it should be visually inspected under natural light (avoid direct sunlight). If visible foreign matter is present, it should not be used. If it is found that there are cracks in the bottle mouth, loose seal, gas leakage, discoloration of the solution, turbidity, mildew or cotton-like hyphae, it is strictly prohibited.
 
3. The osmolality of this product is: 270 ~ 320mOsmol / kg.
 
[Pregnant women and lactating women] Pregnant women and lactating women should be cautious when using this product.
 
[Children's medication] Children's medication should be cautious, please follow the doctor's instructions.
 
[Geriatric Use] No need to adjust the dose.
 
[Drug interaction] This product is forbidden to be compatible with the following injections:
 
Orotic acid, chloramphenicol, dipyridamole, sorbic acid hydrochloride, atropine sulfate, scopolamine hydrobromide, chlorpromazine hydrochloride, promethazine hydrochloride, ergometrine maleate, procaine hydrochloride, sulfur Sodium pentoxide, phenytoin, chlordiazepoxide, norepinephrine hydrochloride, tetracaine hydrochloride, reserpine, sodium nitroprusside, hyaline, furosemide, sodium diureate, corticotropin, vitamin B12, hydrochloric acid Diphenhydramine, chlorpheniramine maleate, cytochrome C, vancomycin hydrochloride, tetracycline hydrochloride, quinine dihydrochloride, cytarabine hydrochloride, vincristine sulfate, and all vaccines and vaccines. Dopamine hydrochloride, hemostatic and vitamin C injections should be diluted before mixing with this product.
 
[Drug overdose] is not clear.
 
【Pharmacology and Toxicology】
 
Inosine is a normal component of the human body, involved in nucleic acid metabolism, protein synthesis and energy metabolism, and can increase the activity of coenzyme A and pyruvate oxidase, so that cells can be normally metabolized under hypoxia. Inosine contributes to the recovery of damaged hepatocyte function.
 
[Pharmacokinetics] is not clear.
 
[Storage] shading, sealed (10 ~ 30 ° C) preservation.
 
[Package] Sodium calcium glass infusion bottle, 250ml per bottle; 100ml per bottle.
 
[Validity] 24 months
 
[Executive Standards] The first edition of the 2015 edition
 
【Approval Number】
 
(1) National medicine quasi-word H20030765 (250ml: inosine 0.6g and glucose 12.5g)
 
(2) National medicine quasi-word H20050928 (100ml: inosine 0.6g and glucose 5.0g)
 
【manufacturer】
 
Company Name: Guangdong Pi Di Pharmaceutical Co., Ltd.
  Production address: No. 66, Pidi Avenue, Yueshan Town, Kaiping City, Guangdong Province
  Postal code: 529331
  Phone number: 0750-2789348
 
400-8899-328 (National Service Phone)
  Fax number: 0750-2789348
  Website: http://www.pdpharm.com
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